Optimizing the Dual-Channel Drug Distribution Path of Medical Insurance Using Graph Attention Network

Main Article Content

M. Dong
Y. R. Che
Y. Z. Wang
Q. Z. Qiao

Abstract

Efficient path planning for dual-channel medical insurance drug distribution requires adaptive coordination among heterogeneous nodes under dynamic inventory, demand, and policy constraints. This study proposes a graph attention network (GAT)-based optimization framework that models hospitals, pharmacies, warehouses, and distribution hubs as a directed weighted graph and integrates multi-head attention with reinforcement learning to achieve intelligent path scheduling. The attention mechanism dynamically captures inter-node dependencies and learns context-aware representations, while the reinforcement learning scheduler continuously updates routing decisions according to realtime network states. Experimental evaluation demonstrates that the proposed approach reduces the average delivery time from 54.9 min to 37.3 min, increases the demand fulfillment rate to 92.1%, and lowers the overall operational cost by 29.8%, while significantly improving inventory coordination and response efficiency at high-demand nodes. The framework provides robust dynamic optimization capabilities for large-scale distribution networks and offers a transferable graph-based resource allocation strategy for intelligent communication infrastructures, where efficient information propagation, network topology optimization, and adaptive routing are critical to electromagnetic information transmission and distributed system management.

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How to Cite
Dong, M., Che, Y. R., Wang, Y. Z., & Qiao, Q. Z. (2026). Optimizing the Dual-Channel Drug Distribution Path of Medical Insurance Using Graph Attention Network. Advanced Electromagnetics, 15(3), 1287–1296. https://doi.org/10.7716/aem.v15i3.3176
Section
Research Articles

References

M. Dong, Y. Che, Y. Wang, and Q. Qiao, “Construction of a precise supervision mechanism for medical insurance dual-channel drugs based on collaborative filtering algorithm in the era of intelligent medical insurance,” J. COMBIN. MATH. COMBIN. COMPUT, vol. 127, pp. 5315-5331, 2025, doi: 10.61091/jcmcc127b-294.

View Article

H. Kong, “Design and application of a "dual-channel" drug management system based on hospital information system,” Journal of Computational Methods in Sciences and Engineering, pp. 14727978251371193, 2025, doi: 10.1177/14727978251371193.

View Article

X. Zhu, H. Hu, and D. Yao, “Exploring community pharmacy manager/pharmacist perceptions and responses to China’s dual-channel policy for improving access and rational use of innovative drugs: a qualitative study,” International Journal of Clinical Pharmacy, pp. 1-10, 2025, doi: 10.1007/s11096-025-01957-5.

View Article

Z. Qin, S. Xu, Q. Li, X. Guan, M. He, and M. Zhou, “Quantitative evaluation of dual-channel drug supply policy on nationally negotiated anti-tumor drugs in Xuzhou: based on interrupted time series analysis,” Frontiers in Pharmacology, vol. 16, pp. 1571822, 2025, doi: 10.3389/fphar.2025.1571822.

View Article

S. Li, Y. Li, Q. Kong, X. Feng, Y. Long, and N. Zhou, “Pricing of medical services and channel selection strategies for pharmaceutical supply chain under the zero-markup drug policy,” Managerial and Decision Economics, vol. 45, no. 8, pp. 5883-5898, 2024, doi: 10.1002/mde.4357.

View Article

L. Huang and Y. Wu, “Research on coordination of a pharmaceutical dual-channel supply chain considering pharmaceutical product quality and sales efforts,” Open Journal of Social Sciences, vol. 10, no. 5, pp. 297-328, 2022, doi: 10.4236/jss.2022.105020.

View Article

J. T. Shi and L. H. Sun, “Research on the Joint Reformation for Public Health Services, Medical Insurance and Medical Production Circulation from the Perspective of System Science,” Asian Social Pharmacy, vol. 19, no. 3, pp. 209-215, 2024.

G. Yang and X. He, “Enhancing the efficacy of pharmaceutical E-commerce through omni-channel coordination,” International Journal of Information Systems and Supply Chain Management (IJISSCM), vol. 16, no. 1, pp. 1-20, 2023, doi: 10.4018/IJISSCM.330147.

View Article

X. LI and J. XU, “Dilemma and promotion strategy of "dual channel" management policy for China’s medical insurance negotiated drugs,” China Pharmacy, pp. 906-911, 2024.

X. T. Hu, B. B. Chen, L. Dong, and L. H. Sun, “Research on the Problems and Countermeasures of the Landing of Negotiated Drugs,” Asian Social Pharmacy, vol. 19, no. 3, pp. 225-231, 2024.

G. Yang, “Determinants of Business Model Choices for New Entrant in the Pharmaceutical E-commerce Environment,” SAGE Open, vol. 14, no. 4, pp. 21582440241295813, 2024, doi: 10.1177/21582440241295813.

View Article

Y. Li and Z. Huang, “Comparison of the Development Model of DTP Pharmacy between China and the United States and Its Enlightenment,” Asian Social Pharmacy, vol. 19, no. 2, pp. 168-177, 2024.

Y. Wen and L. Liu, “Comparative study on low-carbon strategy and government subsidy model of pharmaceutical supply chain,” Sustainability, vol. 15, no. 10, pp. 8345, 2023, doi: 10.3390/su15108345.

View Article

X. Z. Gan, “Digital Transformation Trend of the Pharmaceutical Distribution Industry in the Context of New Infrastructure in China,” Asian Social Pharmacy, vol. 19, no. 2, pp. 159-167, 2024.

J. Liu, Z. Zhao, and M. Hu, “HPR141 Model Analysis on Budget Impact and Patients’ Burden of National Price-Negotiated Drugs and Different Reimbursement Payment Modes in China: Hyperkalemia As an Example,” Value in Health, vol. 27, no. 6, pp. S218-S219, 2024, doi: 10.1016/j.jval.2024.03.2372.

View Article

C. R. Da, P. Narvekar, and P. Okorozo, “HPR116 Do US Managed Care Organizations Restrict Coverage More Than the Food and Drug Administration Label?,” Value in Health, vol. 27, no. 6, pp. S214-S215, 2024, doi: 10.1016/j.jval.2024.03.1185.

View Article

M. You, Z. Zhang, and Y. Shi, “The incentives for information sharing and online expansion strategy in medical supply chains,” RAIRO-Operations Research, vol. 59, no. 1, pp. 653-682, 2025, doi: 10.1051/ro/2025001.

View Article

J. Liu, Z. Zhao, and M. Hu, “HPR83 The Distribution and Influential Factors Analysis of National Price-Negotiated Drugs in Medical Institutions and Pharmacies in China: A Case Study of Hyperkalemia,” Value in Health, vol. 27, no. 6, pp. S208-S209, 2024, doi: 10.1016/j.jval.2024.03.1152.

View Article

M. Taherifar, N. Hasani, M. Zokaee, A. Aghsami, and F. Jolai, “A scenario-based sustainable dual-channel closed-loop supply chain design with pickup and delivery considering social conditions in a natural disaster under uncertainty: a real-life case study,” Environment, Development and Sustainability, vol. 26, no. 8, pp. 19443-19490, 2024, doi: 10.1007/s10668-023-03421-8.

View Article

S. M. Hosseini-Motlagh, M. Johari, M. Nematollahi, and P. Pazari, “Reverse supply chain management with dual channel and collection disruptions: Supply chain coordination and game theory approaches,” Annals of Operations Research, vol. 324, no. 1, pp. 215-248, 2023, doi: 10.1007/s10479-022-04909-8.

View Article

X. Mo, Z. Huang, Y. Xing, and C. Lv, “Multi-agent trajectory prediction with heterogeneous edge-enhanced graph attention network,” IEEE Transactions on Intelligent Transportation Systems, vol. 23, no. 7, pp. 9554-9567, 2022, doi: 10.1109/TITS.2022.3146300.

View Article

Z. Li, T. Zhong, D. Huang, Z. H. You, and R. Nie, “Hierarchical graph attention network for miRNA-disease association prediction,” Molecular Therapy, vol. 30, no. 4, pp. 1775-1786, 2022, doi: 10.1016/j.ymthe.2022.01.041.

View Article

H. Gao, J. Xiao, Y. Yin, T. Liu, and J. Shi, “A mutually supervised graph attention network for few-shot segmentation: The perspective of fully utilizing limited samples,” IEEE Transactions on neural networks and learning systems, vol. 35, no. 4, pp. 4826-4838, 2022, doi: 10.1109/TNNLS.2022.3155486.

View Article

J. Li, J. Wang, H. Lv, Z. Zhang, and Z. Wang, “IMCHGAN: inductive matrix completion with heterogeneous graph attention networks for drug-target interactions prediction,” IEEE/ACM transactions on computational biology and bioinformatics, vol. 19, no. 2, pp. 655-665, 2021, doi: 10.1109/TCBB.2021.3088614.

View Article

N. Jiang, J. Wen, J. Li, X. Liu, and D. Jin, “Gatrust: A multi-aspect graph attention network model for trust assessment in osns,” IEEE Transactions on Knowledge and Data Engineering, vol. 35, no. 6, pp. 5865-5878, 2022, doi: 10.1109/TKDE.2022.3174044.

View Article

D. Ahmedt-Aristizabal, M. A. Armin, S. Denman, C. Fookes, and L. Petersson, “Graph-based deep learning for medical diagnosis and analysis: past, present and future,” Sensors, vol. 21, no. 14, pp. 4758, 2021, doi: 10.3390/s21144758.

View Article

D. Wen, L. Dou, Y. Sun, and S. Wang, “Investigation on the current situation of China’s DTP pharmacy and suggestions for its development,” Asian Social Pharmacy, vol. 18, no. 2, pp. 165-176, 2023.

A. S. Raikar, P. Kumar, G. V. S. Raikar, and S. N. Somnache, “Advances and challenges in IoT-based smart drug delivery systems: a comprehensive review,” Applied System Innovation, vol. 6, no. 4, pp. 62, 2023, doi: 10.3390/asi6040062.

View Article

Y. Tan and C. Guo, “A dual-channel secondary closed-loop supply chain considering retail groups and fairness concerns,” Plos one, vol. 18, no. 10, pp. e0292753, 2023, doi: 10.1371/journal.pone.0292753.

View Article

J. Hu, W. Kang, J. Guo, J. Xu, H. Tang, D. Zhao, and G. Zhang, “Analysis of PLWH switching to medical insurance ART: a cross-sectional study in six Chinese provinces,” BMC Public Health, vol. 24, no. 1, pp. 3361, 2024, doi: 10.1186/s12889-024-20728-x.

View Article

Y. Liu, L. Gou, Z. Guo, Z. Wu, Q. He, and H. Feng, “Evaluation of the implementation effect of hepatitis C medical insurance reimbursement policy in China: A RWS based on medical institutions,” Frontiers in Public Health, vol. 10, pp. 1072493, 2023, doi: 10.3389/fpubh.2022.1072493.

View Article

R. Chauhan and A. Majumder, “Involvement of carbon regulation in a smart dual-channel supply chain for customized products under uncertain environment,” Environment, Development and Sustainability, vol. 27, no. 3, pp. 6997-7032, 2025, doi: 10.1007/s10668-023-04178-w.

View Article

A. Mostofi, V. Jain, Y. Mei, and L. Benyoucef, “A new pricing mechanism for pharmaceutical supply chains: a game theory analytical approach for healthcare service,” International Journal of Logistics Research and Applications, vol. 27, no. 7, pp. 1228-1250, 2024, doi: 10.1080/13675567.2022.2122421.

View Article

A. M. Vargason, A. C. Anselmo, and S. Mitragotri, “The evolution of commercial drug delivery technologies,” Nature biomedical engineering, vol. 5, no. 9, pp. 951-967, 2021, doi: 10.1038/s41551-021-00698-w.

View Article

L. K. Vora, A. D. Gholap, K. Jetha, R. R. S. Thakur, H. K. Solanki, and V. P. Chavda, “Artificial intelligence in pharmaceutical technology and drug delivery design,” Pharmaceutics, vol. 15, no. 7, pp. 1916, 2023, doi: 10.3390/pharmaceutics15071916.

View Article

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